DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage

Oncolytic virotherapy is a promising therapeutic strategy that uses replication-competent viruses to selectively destroy malignancies. However, the therapeutic effect of certain oncolytic viruses (OVs) varies among cancer patients. Thus, it is necessary to overcome resistance to OVs through rational...

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Detalles Bibliográficos
Autores principales: Xiao, Xiao, Liang, Jiankai, Huang, Chunlong, Li, Kai, Xing, Fan, Zhu, Wenbo, Lin, Ziqing, Xu, Wencang, Wu, Guangen, Zhang, Jifu, Lin, Xi, Tan, Yaqian, Cai, Jing, Hu, Jun, Chen, Xueqin, Huang, Youwei, Qin, Zixi, Qiu, Pengxin, Su, Xingwen, Chen, Lijun, Lin, Yuan, Zhang, Haipeng, Yan, Guangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194050/
https://www.ncbi.nlm.nih.gov/pubmed/30337542
http://dx.doi.org/10.1038/s41467-018-06771-4

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