Chronic kidney failure mineral bone disorder leads to a permanent loss of hematopoietic stem cells through dysfunction of the stem cell niche

In chronic kidney disease (CKD), endothelial injury, is associated with disease progression and an increased risk for cardiovascular complications. Circulating cells with vascular reparative functions are hematopoietic and also reduced in CKD. To explore the mechanistic basis behind these observatio...

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Detalles Bibliográficos
Autores principales: Aleksinskaya, Marina A., Monge, Matthieu, Siebelt, Michiel, Slot, Edith M., Koekkoek, Karin M., de Bruin, Ruben G., Massy, Ziad A., Weinans, Harrie, Rabelink, Ton J., Fibbe, Willem E., van Zonneveld, Anton Jan, van Pel, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194087/
https://www.ncbi.nlm.nih.gov/pubmed/30337617
http://dx.doi.org/10.1038/s41598-018-33979-7

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