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Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation

Autophagy is a vital process that involves degradation of long-lived proteins and dysfunctional organelles and contributes to cellular metabolism. Glioma-initiating cells (GICs) have the ability to self-renew, differentiate into heterogeneous types of tumor cells, and sustain tumorigenicity; thus, G...

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Detalles Bibliográficos
Autores principales:	Tao, Zhennan, Li, Tao, Ma, Haiwen, Yang, Yihan, Zhang, Chen, Hai, Long, Liu, Peidong, Yuan, Feng, Li, Jiabo, Yi, Li, Tong, Luqing, Wang, Yingshuai, Xie, Yang, Ming, Haolang, Yu, Shengping, Yang, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194143/ https://www.ncbi.nlm.nih.gov/pubmed/30337536 http://dx.doi.org/10.1038/s41419-018-0957-3

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