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Co-stimulation With TLR7 Agonist Imiquimod and Inactivated Influenza Virus Particles Promotes Mouse B Cell Activation, Differentiation, and Accelerated Antigen Specific Antibody Production

Current influenza vaccines have relatively low effectiveness, especially against antigenically drifted strains, the effectiveness is even lower in the elderly and immunosuppressed individuals. We have previously shown in a randomized clinical trial that the topical application of a toll-like recepto...

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Detalles Bibliográficos
Autores principales:	Li, Can, To, Kelvin K. W., Zhang, Anna J. X., Lee, Andrew C. Y., Zhu, Houshun, Mak, Winger W. N., Hung, Ivan F. N., Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194170/ https://www.ncbi.nlm.nih.gov/pubmed/30369932 http://dx.doi.org/10.3389/fimmu.2018.02370

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