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SeqOthello: querying RNA-seq experiments at scale

We present SeqOthello, an ultra-fast and memory-efficient indexing structure to support arbitrary sequence query against large collections of RNA-seq experiments. It takes SeqOthello only 5 min and 19.1 GB memory to conduct a global survey of 11,658 fusion events against 10,113 TCGA Pan-Cancer RNA-s...

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Detalles Bibliográficos
Autores principales:	Yu, Ye, Liu, Jinpeng, Liu, Xinan, Zhang, Yi, Magner, Eamonn, Lehnert, Erik, Qian, Chen, Liu, Jinze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194578/ https://www.ncbi.nlm.nih.gov/pubmed/30340508 http://dx.doi.org/10.1186/s13059-018-1535-9

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