Considerations for adaptive design in pediatric clinical trials: study protocol for a systematic review, mixed-methods study, and integrated knowledge translation plan

BACKGROUND: Although children have historically been excluded from clinical trials (CTs), many require medicines tested and approved in CTs, forcing health care providers to treat their pediatric patients based on extrapolated data. Unfortunately, traditional randomized CTs can be slow and resource-...

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Detalles Bibliográficos
Autores principales: Kelly, Lauren E, Dyson, Michele P, Butcher, Nancy J, Balshaw, Robert, London, Alex John, Neilson, Christine J, Junker, Anne, Mahmud, Salaheddin M, Driedger, S Michelle, Wang, Xikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194696/
https://www.ncbi.nlm.nih.gov/pubmed/30340624
http://dx.doi.org/10.1186/s13063-018-2934-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194696/
https://www.ncbi.nlm.nih.gov/pubmed/30340624
http://dx.doi.org/10.1186/s13063-018-2934-7

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