Nonspecific Uptake of (68)Ga-Prostate-Specific Membrane Antigen in Diseases other than Prostate Malignancy on Positron Emission Tomography/Computed Tomography Imaging: A Pictorial Assay and Review of Literature

(68)Ga-labeled prostate-specific membrane antigen (PSMA) ligand positron emission tomography/computed tomography imaging (PET/CT) is a rapidly evolving imaging modality for prostate cancer. Many studies have proved its superiority in staging, restaging, and detecting the recurrent prostate cancer. H...

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Detalles Bibliográficos
Autores principales: Malik, Dharmender, Sood, Apurva, Mittal, Bhagwant Rai, Singh, Harmandeep, Basher, Rajender Kumar, Shukla, Jaya, Bhattacharya, Anish, Singh, Shrawan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Pictorial Essay
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194764/
https://www.ncbi.nlm.nih.gov/pubmed/30386054
http://dx.doi.org/10.4103/ijnm.IJNM_81_18
Descripción
Sumario:(68)Ga-labeled prostate-specific membrane antigen (PSMA) ligand positron emission tomography/computed tomography imaging (PET/CT) is a rapidly evolving imaging modality for prostate cancer. Many studies have proved its superiority in staging, restaging, and detecting the recurrent prostate cancer. However, case reports describing the incidental tracer uptake in benign and nonprostatic malignancies are also reported in the literature, thus questioning the specificity of the tracer. This pictorial assay illustrates the nonspecific tracer uptake encountered during PSMA PET/CT imaging, knowledge of which can increase the confidence of interpreting physicians and may also open a new path for peptide receptor radionuclide therapy in nonprostatic malignancies.

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