Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma

Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radiol...

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Detalles Bibliográficos
Autores principales: Sankar, Gowri, Rajaraman, Vishnukumar, Ganesh, Rajesh Nachiappa, Halanaik, Dhanapathi, Pandit, Nandini, Ponnusamy, Madhusudhanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194765/
https://www.ncbi.nlm.nih.gov/pubmed/30386061
http://dx.doi.org/10.4103/ijnm.IJNM_54_18
Descripción
Sumario:Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radioligands such as (99m)Tc labeled hydrazinonicotinyl-Tyr3-octreotide (HYNIC-TOC). The percentage of malignant transformation in laryngeal paraganglioma is 2%, and they usually metastasize to lymph nodes, bone, and liver. Here, we report a (99m)Tc HYNIC-TOC scan of a 55-year-old male patient with recurrent laryngeal paraganglioma, who presented with painful multiple metastatic cutaneous nodules.

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