Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma

Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radiol...

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Autores principales: Sankar, Gowri, Rajaraman, Vishnukumar, Ganesh, Rajesh Nachiappa, Halanaik, Dhanapathi, Pandit, Nandini, Ponnusamy, Madhusudhanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194765/
https://www.ncbi.nlm.nih.gov/pubmed/30386061
http://dx.doi.org/10.4103/ijnm.IJNM_54_18
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author Sankar, Gowri
Rajaraman, Vishnukumar
Ganesh, Rajesh Nachiappa
Halanaik, Dhanapathi
Pandit, Nandini
Ponnusamy, Madhusudhanan
author_facet Sankar, Gowri
Rajaraman, Vishnukumar
Ganesh, Rajesh Nachiappa
Halanaik, Dhanapathi
Pandit, Nandini
Ponnusamy, Madhusudhanan
author_sort Sankar, Gowri
collection PubMed
description Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radioligands such as (99m)Tc labeled hydrazinonicotinyl-Tyr3-octreotide (HYNIC-TOC). The percentage of malignant transformation in laryngeal paraganglioma is 2%, and they usually metastasize to lymph nodes, bone, and liver. Here, we report a (99m)Tc HYNIC-TOC scan of a 55-year-old male patient with recurrent laryngeal paraganglioma, who presented with painful multiple metastatic cutaneous nodules.
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spelling pubmed-61947652018-10-31 Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma Sankar, Gowri Rajaraman, Vishnukumar Ganesh, Rajesh Nachiappa Halanaik, Dhanapathi Pandit, Nandini Ponnusamy, Madhusudhanan Indian J Nucl Med Case Report Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radioligands such as (99m)Tc labeled hydrazinonicotinyl-Tyr3-octreotide (HYNIC-TOC). The percentage of malignant transformation in laryngeal paraganglioma is 2%, and they usually metastasize to lymph nodes, bone, and liver. Here, we report a (99m)Tc HYNIC-TOC scan of a 55-year-old male patient with recurrent laryngeal paraganglioma, who presented with painful multiple metastatic cutaneous nodules. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6194765/ /pubmed/30386061 http://dx.doi.org/10.4103/ijnm.IJNM_54_18 Text en Copyright: © 2018 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sankar, Gowri
Rajaraman, Vishnukumar
Ganesh, Rajesh Nachiappa
Halanaik, Dhanapathi
Pandit, Nandini
Ponnusamy, Madhusudhanan
Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title_full Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title_fullStr Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title_full_unstemmed Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title_short Multiple Cutaneous Metastases on (99m)TC-HYNIC-TOC Scan in a Rare Case of Malignant Laryngeal Paraganglioma
title_sort multiple cutaneous metastases on (99m)tc-hynic-toc scan in a rare case of malignant laryngeal paraganglioma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194765/
https://www.ncbi.nlm.nih.gov/pubmed/30386061
http://dx.doi.org/10.4103/ijnm.IJNM_54_18
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