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Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing
Spiral waves are observed in wide variety of reaction-diffusion systems. Those observed in cardiac tissues are important since they are related to serious disease that threatens human lives, such as atrial or ventricular fibrillation. We consider the unpinning of spiral waves anchored to a circular...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society of Japan (BSJ)
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194964/ https://www.ncbi.nlm.nih.gov/pubmed/30349804 http://dx.doi.org/10.2142/biophysico.15.0_196 |
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author | Kitahata, Hiroyuki Tanaka, Masanobu |
author_facet | Kitahata, Hiroyuki Tanaka, Masanobu |
author_sort | Kitahata, Hiroyuki |
collection | PubMed |
description | Spiral waves are observed in wide variety of reaction-diffusion systems. Those observed in cardiac tissues are important since they are related to serious disease that threatens human lives, such as atrial or ventricular fibrillation. We consider the unpinning of spiral waves anchored to a circular obstacle on excitable media using high-frequency pacing. Here, we consider two types of the obstacle; i.e., that without any diffusive interaction with the environment, and that with diffusive interaction. We found that the threshold frequency for success in unpinning is lower for the obstacle with diffusive interaction than for the one without it. We discuss the threshold frequency based on the angular velocity of a chemical wave anchoring the obstacle. |
format | Online Article Text |
id | pubmed-6194964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Biophysical Society of Japan (BSJ) |
record_format | MEDLINE/PubMed |
spelling | pubmed-61949642018-10-22 Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing Kitahata, Hiroyuki Tanaka, Masanobu Biophys Physicobiol Review Article Spiral waves are observed in wide variety of reaction-diffusion systems. Those observed in cardiac tissues are important since they are related to serious disease that threatens human lives, such as atrial or ventricular fibrillation. We consider the unpinning of spiral waves anchored to a circular obstacle on excitable media using high-frequency pacing. Here, we consider two types of the obstacle; i.e., that without any diffusive interaction with the environment, and that with diffusive interaction. We found that the threshold frequency for success in unpinning is lower for the obstacle with diffusive interaction than for the one without it. We discuss the threshold frequency based on the angular velocity of a chemical wave anchoring the obstacle. The Biophysical Society of Japan (BSJ) 2018-09-12 /pmc/articles/PMC6194964/ /pubmed/30349804 http://dx.doi.org/10.2142/biophysico.15.0_196 Text en 2018 © The Biophysical Society of Japan This article is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-sa/4.0/. |
spellingShingle | Review Article Kitahata, Hiroyuki Tanaka, Masanobu Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title | Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title_full | Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title_fullStr | Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title_full_unstemmed | Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title_short | Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
title_sort | mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194964/ https://www.ncbi.nlm.nih.gov/pubmed/30349804 http://dx.doi.org/10.2142/biophysico.15.0_196 |
work_keys_str_mv | AT kitahatahiroyuki mathematicalapproachtounpinningofspiralwavesanchoredtoanobstaclewithhighfrequencypacing AT tanakamasanobu mathematicalapproachtounpinningofspiralwavesanchoredtoanobstaclewithhighfrequencypacing |