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Mutational analysis of the conserved carboxylates of anion channelrhodopsin-2 (ACR2) expressed in Escherichia coli and their roles in anion transport

Anion channelrhodopsin-2 (ACR2), a light-gated channel recently identified from the cryptophyte alga Guillardia theta, exhibits anion channel activity with exclusive selectivity. In addition to its novel function, ACR2 has become a focus of interest as a powerful tool for optogenetics. Here we combi...

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Detalles Bibliográficos
Autores principales: Kojima, Keiichi, Watanabe, Hiroshi C., Doi, Satoko, Miyoshi, Natsuki, Kato, Misaki, Ishikita, Hiroshi, Sudo, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194965/
https://www.ncbi.nlm.nih.gov/pubmed/30349802
http://dx.doi.org/10.2142/biophysico.15.0_179

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