Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Cohesin is important for 3-dimensional (3D) genome organization. Nevertheless, even the complete removal of cohesin has surprisingly little impact on steady-state gene transcription and enhancer activity. Here we show that cohesin was required for the core transcriptional response of primary macroph...

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Detalles Bibliográficos
Autores principales: Cuartero, Sergi, Weiss, Felix D., Dharmalingam, Gopuraja, Guo, Ya, Ing-Simmons, Elizabeth, Masella, Silvia, Robles-Rebollo, Irene, Xiao, Xiaolin, Wang, Yi-Fang, Barozzi, Iros, Djeghloul, Dounia, Amano, Mariane T., Niskanen, Henri, Petretto, Enrico, Dowell, Robin D., Tachibana, Kikuë, Kaikkonen, Minna U., Nasmyth, Kim A., Lenhard, Boris, Natoli, Gioacchino, Fisher, Amanda G., Merkenschlager, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195188/
https://www.ncbi.nlm.nih.gov/pubmed/30127433
http://dx.doi.org/10.1038/s41590-018-0184-1

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