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Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma

Aberrant expression of proteins involved in cell division is a constant feature in multiple myeloma (MM), especially in high-risk disease. Increasingly, therapy of myeloma is moving towards individualization based on underlying genetic abnormalities. Aurora kinases are important mediators of cell cy...

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Detalles Bibliográficos
Autores principales: Painuly, Utkarsh, Ramakrishnan, Vijay, Kimlinger, Teresa, Wellik, Linda, Haug, Jessica, Gonsalves, Wilson, Bi, Lintao, Huang, Zhongxia, Rajkumar, S. Vincent, Kumar, Shaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195373/
https://www.ncbi.nlm.nih.gov/pubmed/30349651
http://dx.doi.org/10.18632/oncotarget.26180