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Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma
Aberrant expression of proteins involved in cell division is a constant feature in multiple myeloma (MM), especially in high-risk disease. Increasingly, therapy of myeloma is moving towards individualization based on underlying genetic abnormalities. Aurora kinases are important mediators of cell cy...
Autores principales: | Painuly, Utkarsh, Ramakrishnan, Vijay, Kimlinger, Teresa, Wellik, Linda, Haug, Jessica, Gonsalves, Wilson, Bi, Lintao, Huang, Zhongxia, Rajkumar, S. Vincent, Kumar, Shaji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195373/ https://www.ncbi.nlm.nih.gov/pubmed/30349651 http://dx.doi.org/10.18632/oncotarget.26180 |
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