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Targeting enhancer of zeste homolog 2 protects against acute kidney injury

Despite the established oncogenic and profibrotic functions of enhancer of zeste homolog 2 (EZH2), a methyltransferase that induces histone H3 lysine 27 trimethylation (H3K27me3), its role in acute kidney injury (AKI) remains unclear. In this study, we demonstrated that EZH2 and H3K27me3 were upregu...

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Detalles Bibliográficos
Autores principales:	Zhou, X., Zang, X., Guan, Y., Tolbert, T., Zhao, T. C., Bayliss, G., Zhuang, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195522/ https://www.ncbi.nlm.nih.gov/pubmed/30341286 http://dx.doi.org/10.1038/s41419-018-1012-0

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