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Mutational interactions define novel cancer subgroups

Large-scale genomic data highlight the complexity and diversity of the molecular changes that drive cancer progression. Statistical analysis of cancer data from different tissues can guide drug repositioning as well as the design of targeted treatments. Here, we develop an improved Bayesian network...

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Detalles Bibliográficos
Autores principales: Kuipers, Jack, Thurnherr, Thomas, Moffa, Giusi, Suter, Polina, Behr, Jonas, Goosen, Ryan, Christofori, Gerhard, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195543/
https://www.ncbi.nlm.nih.gov/pubmed/30341300
http://dx.doi.org/10.1038/s41467-018-06867-x