Cargando…

A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites

Although vasculo-protective effects of flavan-3-ols are widely accepted today, their impact on endothelial cell functions and molecular mechanisms of action involved is not completely understood. The aim of this study was to characterize the potential endothelium-protective effects of circulating ep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milenkovic, Dragan, Berghe, Wim Vanden, Morand, Christine, Claude, Sylvain, van de Sandt, Annette, Gorressen, Simone, Monfoulet, Laurent-Emmanuel, Chirumamilla, Chandra S., Declerck, Ken, Szic, Katarzyna Szarc vel, Lahtela-Kakkonen, Maija, Gerhauser, Clarissa, Merx, Marc W., Kelm, Malte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195584/ https://www.ncbi.nlm.nih.gov/pubmed/30341379 http://dx.doi.org/10.1038/s41598-018-33959-x

Ejemplares similares

From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
por: vel Szic, Katarzyna Szarc, et al.
Publicado: (2015)

Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A
por: vel Szic, Katarzyna Szarc, et al.
Publicado: (2017)

Flavanol Consumption in Healthy Men Preserves Integrity of Immunological‐Endothelial Barrier Cell Functions: Nutri(epi)genomic Analysis
por: Milenkovic, Dragan, et al.
Publicado: (2022)

Whole-Genome Saliva and Blood DNA Methylation Profiling in Individuals with a Respiratory Allergy
por: Langie, Sabine A. S., et al.
Publicado: (2016)

Correction: Whole-Genome Saliva and Blood DNA Methylation Profiling in Individuals with a Respiratory Allergy
por: Langie, Sabine A. S., et al.
Publicado: (2017)

Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease
por: Istas, Geoffrey, et al.
Publicado: (2017)

Dietary Flavanols Modulate the Transcription of Genes Associated with Cardiovascular Pathology without Changes in Their DNA Methylation State
por: Milenkovic, Dragan, et al.
Publicado: (2014)

Impact of Epicatechin on the Procoagulant Activities of Microparticles
por: Sinegre, Thomas, et al.
Publicado: (2020)

Pharmacological Levels of Withaferin A (Withania somnifera) Trigger Clinically Relevant Anticancer Effects Specific to Triple Negative Breast Cancer Cells
por: Szarc vel Szic, Katarzyna, et al.
Publicado: (2014)

DNA methylation of candidate genes in peripheral blood from patients with type 2 diabetes or the metabolic syndrome
por: van Otterdijk, Sanne D., et al.
Publicado: (2017)

PE and PET oligomers’ interplay with membrane bilayers
por: Järvenpää, Joni, et al.
Publicado: (2022)

The Role of Nutri(epi)genomics in Achieving the Body’s Full Potential in Physical Activity
por: Petracci, Irene, et al.
Publicado: (2020)

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy
por: Langie, Sabine A. S., et al.
Publicado: (2018)

Metabolic syndrome: Nutri-epigenetic cause or consequence?
por: Silva-Ochoa, Alfonso D., et al.
Publicado: (2023)

Integrated Multi-Omic Analyses of the Genomic Modifications by Gut Microbiome-Derived Metabolites of Epicatechin, 5-(4′-Hydroxyphenyl)-γ-Valerolactone, in TNFalpha-Stimulated Primary Human Brain Microvascular Endothelial Cells
por: Corral-Jara, Karla Fabiola, et al.
Publicado: (2021)

SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors
por: Djokovic, Nemanja, et al.
Publicado: (2023)

Depletion of circulating blood NOS3 increases severity of myocardial infarction and left ventricular dysfunction
por: Merx, Marc W., et al.
Publicado: (2013)

BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses
por: Kokkola, Tarja, et al.
Publicado: (2015)

Circulating NOS3 Modulates Left Ventricular Remodeling following Reperfused Myocardial Infarction
por: Gorressen, Simone, et al.
Publicado: (2015)

Epicatechin Mitigates Anxiety-Related Behavior in a Mouse Model of Obesity by Modulating Gut Microbiome Composition and Global Gene Expression Profile in the Hippocampus
por: Milenkovic, Dragan, et al.
Publicado: (2022)

Characterization of Blood Surrogate Immune-Methylation Biomarkers for Immune Cell Infiltration in Chronic Inflammaging Disorders
por: Declerck, Ken, et al.
Publicado: (2019)

Synthesis and Evaluation of Substituted Chroman-4-one and Chromone Derivatives as Sirtuin 2-Selective Inhibitors
por: Fridén-Saxin, Maria, et al.
Publicado: (2012)

Nutri-Calc HD
por: Mayne, Susan Taylor
Publicado: (1990)

Sirtuin functions and modulation: from chemistry to the clinic
por: Carafa, Vincenzo, et al.
Publicado: (2016)

Evaluating the role of orange juice, HESPERidin in vascular HEALTH benefits (HESPER-HEALTH study): protocol for a randomised controlled trial
por: Verny, Marie-Anne, et al.
Publicado: (2021)

Neuronal NOS-inhibition in the setting of septic cardiomyopathy
por: Sandt, A van de, et al.
Publicado: (2010)

Pharmacological CCR1 blockade limits infarct size and preserves cardiac function in a chronic model of myocardial ischemia/reperfusion
por: Van de Sandt, A, et al.
Publicado: (2011)

Therapeutic uses of epicatechin in diabetes and cancer
por: Abdulkhaleq, Layth Abdulmajeed, et al.
Publicado: (2017)

Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, “selectivity pocket” and NAD(+)-binding site
por: Mellini, Paolo, et al.
Publicado: (2017)

Natural polyphenols as sirtuin 6 modulators
por: Rahnasto-Rilla, Minna, et al.
Publicado: (2018)

The Identification of a SIRT6 Activator from Brown Algae Fucus distichus
por: Rahnasto-Rilla, Minna K., et al.
Publicado: (2017)

2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors
por: Pätsi, Henri T., et al.
Publicado: (2021)

Nutritional Assessment of Ready-to-Eat Salads in German Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score
por: Schlarbaum, Laura, et al.
Publicado: (2022)

Morphologic and Pharmacological Investigations in the Epicatechin Gastroprotective Effect
por: Rozza, A. L., et al.
Publicado: (2012)

Corynanthean-Epicatechin Flavoalkaloids from Corynanthe pachyceras
por: Kouamé, Tapé, et al.
Publicado: (2020)

PXR is a target of (-)-epicatechin in skeletal muscle
por: Ortiz-Flores, Miguel, et al.
Publicado: (2020)

(-)-Epicatechin Is a Biased Ligand of Apelin Receptor
por: Portilla-Martínez, Andrés, et al.
Publicado: (2022)

Establishment of a New Murine Elastase-Induced Aneurysm Model Combined with Transplantation
por: Rowinska, Zuzanna, et al.
Publicado: (2014)

Using the Sleeve Technique in a Mouse Model of Aortic Transplantation - An Instructional Video
por: Rowinska, Zuzanna, et al.
Publicado: (2017)

Endothelial nitric oxide synthase deficiency and inducible nitric oxide synthase inhibition in the setting of septic cardiomyopathy
por: Sandt, A Van de, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_omkhprcoa22c9561jbnqndbgru