Cargando…
Dissecting the role of His domain protein tyrosine phosphatase/PTPN23 and ESCRTs in sorting activated epidermal growth factor receptor to the multivesicular body
Sorting of activated epidermal growth factor receptor (EGFR) into intraluminal vesicles (ILVs) within the multivesicular body (MVB) is an essential step during the down-regulation of the receptor. The machinery that drives EGFR sorting attaches to the cytoplasmic face of the endosome and generates v...
Autores principales: | Tabernero, Lydia, Woodman, Philip |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195633/ https://www.ncbi.nlm.nih.gov/pubmed/30190330 http://dx.doi.org/10.1042/BST20170443 |
Ejemplares similares
-
His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation
por: Parkinson, Gabrielle, et al.
Publicado: (2021) -
ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation
por: Edgar, James R., et al.
Publicado: (2015) -
Molecular Mechanism of Multivesicular Body Biogenesis by ESCRT Complexes
por: Wollert, Thomas, et al.
Publicado: (2010) -
The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function
por: Gahloth, Deepankar, et al.
Publicado: (2017) -
Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer
por: Mcheik, Soha, et al.
Publicado: (2020)