Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

BACKGROUND: Cytokines are critical to human disease and are attractive therapeutic targets given their widespread influence on gene regulation and transcription. Defining the downstream regulatory mechanisms influenced by cytokines is central to defining drug and disease mechanisms. One promising st...

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Detalles Bibliográficos
Autores principales: Davenport, Emma E., Amariuta, Tiffany, Gutierrez-Arcelus, Maria, Slowikowski, Kamil, Westra, Harm-Jan, Luo, Yang, Shen, Ciyue, Rao, Deepak A., Zhang, Ying, Pearson, Stephen, von Schack, David, Beebe, Jean S., Bing, Nan, John, Sally, Vincent, Michael S., Zhang, Baohong, Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195724/
https://www.ncbi.nlm.nih.gov/pubmed/30340504
http://dx.doi.org/10.1186/s13059-018-1560-8

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