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MicroRNA-30 modulates metabolic inflammation by regulating notch signaling in adipose tissue macrophages

BACKGROUND/OBJECTIVES: Obesity is a pandemic disorder that is characterized by accumulation of adipose tissue and chronic-low grade inflammation that is driven primarily by adipose tissue macrophages (ATMs). While ATM polarization from pro-(M1)to anti-(M2) inflammatory phenotype influences insulin s...

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Detalles Bibliográficos
Autores principales: Miranda, Kathryn, Yang, Xiaoming, Bam, Marpe, Murphy, E. Angela, Nagarkatti, Prakash S., Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195825/
https://www.ncbi.nlm.nih.gov/pubmed/29899524
http://dx.doi.org/10.1038/s41366-018-0114-1