Cargando…
Targeting PRPK and TOPK for skin cancer prevention and therapy
Solar ultraviolet (sUV) irradiation is a major environmental carcinogen that can cause inflammation and skin cancer. The costs and morbidity associated with skin cancer are increasing, and therefore identifying molecules that can help prevent skin carcinogenesis is important. In this study, we ident...
Autores principales: | Roh, Eunmiri, Lee, Mee-Hyun, Zykova, Tatyana A., Zhu, Feng, Nadas, Janos, Kim, Hong-Gyum, Bae, Ki Beom, Li, Yan, Cho, Yong Yeon, Curiel-Lewandrowski, Clara, Einspahr, Janine, Dickinson, Sally E., Bode, Ann M., Dong, Zigang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195829/ https://www.ncbi.nlm.nih.gov/pubmed/29904102 http://dx.doi.org/10.1038/s41388-018-0350-9 |
Ejemplares similares
-
Crystal structure of the human PRPK–TPRKB complex
por: Li, Jian, et al.
Publicado: (2021) -
Comprehensive Physicochemical Characterization, In Vitro Membrane Permeation, and In Vitro Human Skin Cell Culture of a Novel TOPK Inhibitor, HI-TOPK-032
por: Eedara, Basanth Babu, et al.
Publicado: (2023) -
Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis
por: Kim, Jong-Eun, et al.
Publicado: (2015) -
Protein activation mapping of human sun-protected epidermis after an acute dose of erythemic solar simulated light
por: Einspahr, Janine G., et al.
Publicado: (2017) -
PBK/TOPK: An Effective Drug Target with Diverse Therapeutic Potential
por: Huang, Hai, et al.
Publicado: (2021)