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Quantitative Approaches to Assess Key Carcinogenic Events of Genotoxic Carcinogens

Chemical carcinogenesis is a multistep process. Genotoxic carcinogens, which are DNA-reactive, induce DNA adduct formation and genetic alterations in target cells, thereby generating mutated cells (initiation). Subsequently, preneoplastic lesions appear through clonal proliferation of the mutated ce...

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Detalles Bibliográficos
Autores principales:	Fukushima, Shoji, Gi, Min, Fujioka, Masaki, Kakehashi, Anna, Wanibuchi, Hideki, Matsumoto, Michiharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Toxicology 2018
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195881/ https://www.ncbi.nlm.nih.gov/pubmed/30370003 http://dx.doi.org/10.5487/TR.2018.34.4.291

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