TNER: a novel background error suppression method for mutation detection in circulating tumor DNA

BACKGROUND: Ultra-deep next-generation sequencing of circulating tumor DNA (ctDNA) holds great promise as a tool for the early detection of cancer and for monitoring disease progression and therapeutic responses. However, the low abundance of ctDNA in the bloodstream coupled with technical errors in...

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Detalles Bibliográficos
Autores principales: Deng, Shibing, Lira, Maruja, Huang, Donghui, Wang, Kai, Valdez, Crystal, Kinong, Jennifer, Rejto, Paul A., Bienkowska, Jadwiga, Hardwick, James, Xie, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195972/
https://www.ncbi.nlm.nih.gov/pubmed/30342468
http://dx.doi.org/10.1186/s12859-018-2428-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195972/
https://www.ncbi.nlm.nih.gov/pubmed/30342468
http://dx.doi.org/10.1186/s12859-018-2428-3

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