The race for antimicrobials in the multidrug resistance era

The appearance of multidrug‐resistant pathogens is a major threat to human health with the reemergence of fatal and untreatable diseases. In addition to a rational use of the well‐known and available antibiotics, two complementary ways to overcome this public health issue are (i) the discovery of ne...

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Detalles Bibliográficos
Autores principales: Molina‐Santiago, Carlos, de Vicente, Antonio, Romero, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196379/
https://www.ncbi.nlm.nih.gov/pubmed/29205906
http://dx.doi.org/10.1111/1751-7915.12884
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author Molina‐Santiago, Carlos
de Vicente, Antonio
Romero, Diego
author_facet Molina‐Santiago, Carlos
de Vicente, Antonio
Romero, Diego
author_sort Molina‐Santiago, Carlos
collection PubMed
description The appearance of multidrug‐resistant pathogens is a major threat to human health with the reemergence of fatal and untreatable diseases. In addition to a rational use of the well‐known and available antibiotics, two complementary ways to overcome this public health issue are (i) the discovery of new antimicrobials and (ii) the chemical modification of pre‐existing potent antibiotics. In this article, we highlight some of the strategies to generate new and promising antimicrobials for use in the management of these so‐called ‘superbugs’.
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spelling pubmed-61963792018-10-30 The race for antimicrobials in the multidrug resistance era Molina‐Santiago, Carlos de Vicente, Antonio Romero, Diego Microb Biotechnol Opinion The appearance of multidrug‐resistant pathogens is a major threat to human health with the reemergence of fatal and untreatable diseases. In addition to a rational use of the well‐known and available antibiotics, two complementary ways to overcome this public health issue are (i) the discovery of new antimicrobials and (ii) the chemical modification of pre‐existing potent antibiotics. In this article, we highlight some of the strategies to generate new and promising antimicrobials for use in the management of these so‐called ‘superbugs’. John Wiley and Sons Inc. 2017-12-04 /pmc/articles/PMC6196379/ /pubmed/29205906 http://dx.doi.org/10.1111/1751-7915.12884 Text en © 2017 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Opinion
Molina‐Santiago, Carlos
de Vicente, Antonio
Romero, Diego
The race for antimicrobials in the multidrug resistance era
title The race for antimicrobials in the multidrug resistance era
title_full The race for antimicrobials in the multidrug resistance era
title_fullStr The race for antimicrobials in the multidrug resistance era
title_full_unstemmed The race for antimicrobials in the multidrug resistance era
title_short The race for antimicrobials in the multidrug resistance era
title_sort race for antimicrobials in the multidrug resistance era
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196379/
https://www.ncbi.nlm.nih.gov/pubmed/29205906
http://dx.doi.org/10.1111/1751-7915.12884
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