SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Some exciting biological questions require quantifying thousands of proteins in single cells. To achieve this goal, we develop Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) and validate its ability to identify distinct human cancer cell types based on their proteomes. We use SCoPE-MS to qua...

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Detalles Bibliográficos
Autores principales: Budnik, Bogdan, Levy, Ezra, Harmange, Guillaume, Slavov, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196420/
https://www.ncbi.nlm.nih.gov/pubmed/30343672
http://dx.doi.org/10.1186/s13059-018-1547-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196420/
https://www.ncbi.nlm.nih.gov/pubmed/30343672
http://dx.doi.org/10.1186/s13059-018-1547-5

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