Structural characterization of the D290V mutation site in hnRNPA2 low-complexity–domain polymers

Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2 to valine is believed to predispose patients...

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Detalles Bibliográficos
Autores principales: Murray, Dylan T., Zhou, Xiaoming, Kato, Masato, Xiang, Siheng, Tycko, Robert, McKnight, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196502/
https://www.ncbi.nlm.nih.gov/pubmed/30279180
http://dx.doi.org/10.1073/pnas.1806174115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196502/
https://www.ncbi.nlm.nih.gov/pubmed/30279180
http://dx.doi.org/10.1073/pnas.1806174115

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