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Structural characterization of the D290V mutation site in hnRNPA2 low-complexity–domain polymers
Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2 to valine is believed to predispose patients...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196502/ https://www.ncbi.nlm.nih.gov/pubmed/30279180 http://dx.doi.org/10.1073/pnas.1806174115 |