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Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine
Proliferative gastrointestinal (GI) tissue is radiation-sensitive, and heavy-ion space radiation with its high-linear energy transfer (high-LET) and higher damaging potential than low-LET γ-rays is predicted to compromise astronauts’ GI function. However, much uncertainty remains in our understandin...
Autores principales: | Kumar, Santosh, Suman, Shubhankar, Fornace, Albert J., Datta, Kamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196540/ https://www.ncbi.nlm.nih.gov/pubmed/30275302 http://dx.doi.org/10.1073/pnas.1807522115 |
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