BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?

In this letter, we respond to and discuss the recent publication by Al-Moghrabi et al.: Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters. We discuss their findings with emphasis on two other recently published papers and argue that their data allows...

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Detalles Bibliográficos
Autores principales: Lønning, Per Eystein, Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196557/
https://www.ncbi.nlm.nih.gov/pubmed/30348217
http://dx.doi.org/10.1186/s13148-018-0566-0
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author Lønning, Per Eystein
Knappskog, Stian
author_facet Lønning, Per Eystein
Knappskog, Stian
author_sort Lønning, Per Eystein
collection PubMed
description In this letter, we respond to and discuss the recent publication by Al-Moghrabi et al.: Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters. We discuss their findings with emphasis on two other recently published papers and argue that their data allows no conclusion regarding the transmission of BRCA1 methylation from parent to child.
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spelling pubmed-61965572018-10-30 BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only? Lønning, Per Eystein Knappskog, Stian Clin Epigenetics Letter to the Editor In this letter, we respond to and discuss the recent publication by Al-Moghrabi et al.: Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters. We discuss their findings with emphasis on two other recently published papers and argue that their data allows no conclusion regarding the transmission of BRCA1 methylation from parent to child. BioMed Central 2018-10-22 /pmc/articles/PMC6196557/ /pubmed/30348217 http://dx.doi.org/10.1186/s13148-018-0566-0 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Lønning, Per Eystein
Knappskog, Stian
BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title_full BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title_fullStr BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title_full_unstemmed BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title_short BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
title_sort brca1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196557/
https://www.ncbi.nlm.nih.gov/pubmed/30348217
http://dx.doi.org/10.1186/s13148-018-0566-0
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