Downregulation of RNF138 inhibits cellular proliferation, migration, invasion and EMT in glioma cells via suppression of the Erk signaling pathway

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Glioma is the most common adult malignant primary brain tumor; however, the effect of chemotherapy is often limited by drug-resistance and poor prognosis is common. Ring finger protein 138 (RNF138) belongs to the E3 ligase family, and has significantly higher expression level in glioma tissue than i...

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Detalles Bibliográficos
Autores principales: Wu, Haibin, Li, Xuetao, Feng, Ming, Yao, Lin, Deng, Zhitong, Zao, Guozheng, Zhou, Youxin, Chen, Sansong, Du, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196598/
https://www.ncbi.nlm.nih.gov/pubmed/30272353
http://dx.doi.org/10.3892/or.2018.6744
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