Cargando…

GLP-2 analog teduglutide significantly reduces need for parenteral nutrition and stool frequency in a real-life setting

BACKGROUND: To evaluate the benefits of teduglutide in a real-life setting, we analyzed the data of 14 patients with short bowel syndrome treated with teduglutide. Additionally, we studied glucagon-like peptide 2 (GLP-2) receptor expression in samples of small intestinal and colonic tissue to provid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schoeler, Marc, Klag, Thomas, Wendler, Judith, Bernhard, Simon, Adolph, Michael, Kirschniak, Andreas, Goetz, Martin, Malek, Nisar, Wehkamp, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196620/ https://www.ncbi.nlm.nih.gov/pubmed/30364471 http://dx.doi.org/10.1177/1756284818793343

Ejemplares similares

Ustekinumab is effective in biological refractory Crohn’s disease patients–regardless of approval study selection criteria
por: Saman, Sadik, et al.
Publicado: (2019)

Efficacy and Safety of Teduglutide in Infants and Children With Short Bowel Syndrome Dependent on Parenteral Support
por: Chiba, Masahiro, et al.
Publicado: (2023)

Practical guidance for the management of iron deficiency in patients with inflammatory bowel disease
por: Niepel, Dorothea, et al.
Publicado: (2018)

Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials
por: Seidner, Douglas L., et al.
Publicado: (2019)

Case Report: Morphologic and Functional Characteristics of Intestinal Mucosa in a Child With Short Bowel Syndrome After Treatment With Teduglutide: Evidence in Favor of GLP-2 Analog Safety
por: Falco, Enrico Costantino, et al.
Publicado: (2022)

Endoscopic Balloon Dilation for Crohn’s Disease-Associated Strictures
por: Klag, Thomas, et al.
Publicado: (2017)

Efficacy of Teduglutide for Parenteral Support Reduction in Patients with Short Bowel Syndrome: A Systematic Review and Meta-Analysis
por: Bioletto, Fabio, et al.
Publicado: (2022)

Changes in Parenteral Nutrition Requirements and BMI in Patients with Parenteral Nutrition-Dependent Short Bowel Syndrome after Stopping Teduglutide—9 Years of Follow-Up
por: Zaczek, Zuzanna, et al.
Publicado: (2022)

Teduglutide for short bowel syndrome
Publicado: (2020)

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
por: Jeppesen, P B, et al.
Publicado: (2011)

Teduglutide in amyloidosis‐associated intestinal failure
por: Luhn, Clara, et al.
Publicado: (2023)

Medical Therapy of Perianal Crohn's Disease
por: Klag, Thomas, et al.
Publicado: (2015)

Quality of life in inflammatory bowel diseases: it is not all about the bowel
por: Keller, Ronald, et al.
Publicado: (2021)

Independence From Parenteral Nutrition and Intravenous Fluid Support During Treatment With Teduglutide Among Patients With Intestinal Failure Associated With Short Bowel Syndrome
por: Iyer, Kishore R., et al.
Publicado: (2016)

Bridging intestinal failure with Teduglutide – A case report
por: Schlager, Lukas, et al.
Publicado: (2021)

Teduglutide in short bowel syndrome patients: A way back to normal life?
por: Harpain, Felix, et al.
Publicado: (2021)

Fragmentation of Human Neutrophil α-Defensin 4 to Combat Multidrug Resistant Bacteria
por: Ehmann, Dirk, et al.
Publicado: (2020)

Ethical and legal points of view in parenteral nutrition – Guidelines on Parenteral Nutrition, Chapter 12
por: Rothaermel, S., et al.
Publicado: (2009)

Dose‐dependent elevation in amylase and lipase in response to teduglutide administration
por: Lee, Joshua, et al.
Publicado: (2019)

Use of Teduglutide in Children With Intestinal Failure: A Systematic Review
por: Gigola, Francesca, et al.
Publicado: (2022)

Infantile Stools and Their Significance
Publicado: (1898)

Emerging treatment options for short bowel syndrome: potential role of teduglutide
por: Tee, Cheng T, et al.
Publicado: (2011)

Targeted therapy of short-bowel syndrome with teduglutide: the new kid on the block
por: Vipperla, Kishore, et al.
Publicado: (2014)

Short Bowel Syndrome and Kidney Transplantation: Challenges, Outcomes, and the Use of Teduglutide
por: Abou Diwan, Elizabeth, et al.
Publicado: (2020)

Effect of Teduglutide, a Glucagon-like Peptide 2 Analog, on Citrulline Levels in Patients With Short Bowel Syndrome in Two Phase III Randomized Trials
por: Seidner, Douglas L, et al.
Publicado: (2015)

Platelets in chronic liver disease, from bench to bedside
por: Ramadori, Pierluigi, et al.
Publicado: (2019)

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
por: Ehmann, D., et al.
Publicado: (2019)

Oral GLP1 Analog: Where Does the Tide Go?
por: Gardner, Hannah, et al.
Publicado: (2020)

Long-Term Teduglutide for the Treatment of Patients With Intestinal Failure Associated With Short Bowel Syndrome
por: Schwartz, Lauren K, et al.
Publicado: (2016)

Impact of Teduglutide on Quality of Life Among Patients With Short Bowel Syndrome and Intestinal Failure
por: Chen, Kristina, et al.
Publicado: (2019)

Effects of Teduglutide on Diarrhea in Pediatric Patients with Short Bowel Syndrome-Associated Intestinal Failure
por: Fifi, Amanda, et al.
Publicado: (2023)

Expression, Purification and Characterization of Functional Teduglutide Using GST Fusion System in Prokaryotic Cells
por: Alizadeh, Ali Akbar, et al.
Publicado: (2023)

Intensive medicine – Guidelines on Parenteral Nutrition, Chapter 14
por: Kreymann, G., et al.
Publicado: (2009)

Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function
por: Rowlands, Jordan, et al.
Publicado: (2018)

Energy expenditure and energy intake – Guidelines on Parenteral Nutrition, Chapter 3
por: Kreymann, G., et al.
Publicado: (2009)

Population pharmacokinetics and exposure‐response analyses of teduglutide in adult and pediatric patients with short bowel syndrome
por: Marier, Jean‐Francois, et al.
Publicado: (2021)

A Case Report of Cardiac Failure in a Patient on Teduglutide for High-Output Ileostomy Stoma
por: Nair, Ambica, et al.
Publicado: (2023)

Case report: Exploring teduglutide as a therapeutic option for refractory microscopic colitis: insights and implications
por: Rim, Daniel Sungku, et al.
Publicado: (2023)

Gastric Foveolar Hyperplastic Polyps in 2 Children With Short Bowel Syndrome on Long-Term Teduglutide
por: Salazar, Jonathan A., et al.
Publicado: (2023)

Stool consistency is significantly associated with pain perception
por: Shiro, Yukiko, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_828h7f81kk8nijadctkq6ofkk3