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Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

Axon degeneration occurs in all neurodegenerative diseases, but the molecular pathways regulating axon destruction during neurodegeneration are poorly understood. Sterile Alpha and TIR Motif Containing 1 (Sarm1) is an essential component of the prodegenerative pathway driving axon degeneration after...

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Detalles Bibliográficos
Autores principales:	Peters, Owen M, Lewis, Elizabeth A, Osterloh, Jeannette M, Weiss, Alexandra, Salameh, Johnny S, Metterville, Jake, Brown, Robert H, Freeman, Marc R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196650/ https://www.ncbi.nlm.nih.gov/pubmed/30010873 http://dx.doi.org/10.1093/hmg/ddy260

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