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Retiform Hemangioendothelioma of the Gluteal Region: A Case Report

Retiform hemangioendothelioma is a locally aggressive, rarely metastasizing, low-grade angiosarcoma characterized by intercommunicating vascular channels lined by hobnail or cuboidal endothelial cells, flanked by lymphocyte and hyaline sclerosis. Neoplastic endothelial cells usually express von Will...

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Autores principales: Quadri, Shagufta, Saeed, Noora, Vasenwala, Shaista M., Ansari, Hena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196697/
https://www.ncbi.nlm.nih.gov/pubmed/30787845
http://dx.doi.org/10.4103/sjmms.sjmms_145_16
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author Quadri, Shagufta
Saeed, Noora
Vasenwala, Shaista M.
Ansari, Hena A.
author_facet Quadri, Shagufta
Saeed, Noora
Vasenwala, Shaista M.
Ansari, Hena A.
author_sort Quadri, Shagufta
collection PubMed
description Retiform hemangioendothelioma is a locally aggressive, rarely metastasizing, low-grade angiosarcoma characterized by intercommunicating vascular channels lined by hobnail or cuboidal endothelial cells, flanked by lymphocyte and hyaline sclerosis. Neoplastic endothelial cells usually express von Willebrand factor, CD31 and CD34, while the lymphocytic infiltrate shows a mixture of CD3+, T and CD20+ B cells. The authors describe a case of a 76-year-old female who presented with a soft, painless, ill-defined mass measuring 9 cm in her right gluteal region for the past 15 years, clinically suggestive of a lipoma. There was no regional lymphadenopathy. The mass was resected and sent for histopathological examination. The slow-growing lesion and the typical histomorphology led to the diagnosis of retiform hemangioendothelioma. The diagnosis was confirmed by immunohistochemistry using CD34 antibody, which strongly stained the endothelial cells. The patient was followed up for 6 months after the surgery and no recurrence was noted.
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spelling pubmed-61966972019-02-20 Retiform Hemangioendothelioma of the Gluteal Region: A Case Report Quadri, Shagufta Saeed, Noora Vasenwala, Shaista M. Ansari, Hena A. Saudi J Med Med Sci Case Report Retiform hemangioendothelioma is a locally aggressive, rarely metastasizing, low-grade angiosarcoma characterized by intercommunicating vascular channels lined by hobnail or cuboidal endothelial cells, flanked by lymphocyte and hyaline sclerosis. Neoplastic endothelial cells usually express von Willebrand factor, CD31 and CD34, while the lymphocytic infiltrate shows a mixture of CD3+, T and CD20+ B cells. The authors describe a case of a 76-year-old female who presented with a soft, painless, ill-defined mass measuring 9 cm in her right gluteal region for the past 15 years, clinically suggestive of a lipoma. There was no regional lymphadenopathy. The mass was resected and sent for histopathological examination. The slow-growing lesion and the typical histomorphology led to the diagnosis of retiform hemangioendothelioma. The diagnosis was confirmed by immunohistochemistry using CD34 antibody, which strongly stained the endothelial cells. The patient was followed up for 6 months after the surgery and no recurrence was noted. Medknow Publications & Media Pvt Ltd 2018 2018-08-14 /pmc/articles/PMC6196697/ /pubmed/30787845 http://dx.doi.org/10.4103/sjmms.sjmms_145_16 Text en Copyright: © 2018 Saudi Journal of Medicine & Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Quadri, Shagufta
Saeed, Noora
Vasenwala, Shaista M.
Ansari, Hena A.
Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title_full Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title_fullStr Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title_full_unstemmed Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title_short Retiform Hemangioendothelioma of the Gluteal Region: A Case Report
title_sort retiform hemangioendothelioma of the gluteal region: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196697/
https://www.ncbi.nlm.nih.gov/pubmed/30787845
http://dx.doi.org/10.4103/sjmms.sjmms_145_16
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