Pembrolizumab-induced agranulocytosis in a pulmonary pleomorphic carcinoma patient who developed interstitial lung disease and ocular myasthenia gravis

An 82-year-old man with a recurrence of pulmonary pleomorphic carcinoma was treated with pembrolizumab. He achieved partial response after three cycles of pembrolizumab. However, he developed febrile neutropenia. A bone marrow aspiration sample revealed a decrease of mature neutrophils, and anti-neu...

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Detalles Bibliográficos
Autores principales: Tozuka, Takehiro, Sugano, Teppei, Noro, Rintaro, Takano, Natsuki, Hisakane, Kakeru, Takahashi, Satoshi, Tanaka, Toru, Kashiwada, Takeru, Takeuchi, Susumu, Kunugi, Shinobu, Minegishi, Yuji, Saito, Yoshinobu, Kubota, Kaoru, Seike, Masahiro, Gemma, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196766/
https://www.ncbi.nlm.nih.gov/pubmed/30364514
http://dx.doi.org/10.1093/omcr/omy094

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