Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neur...

Descripción completa

Detalles Bibliográficos
Autores principales: Akinyemi, Ayodele Jacob, Adeniyi, Philip Adeyemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196928/
https://www.ncbi.nlm.nih.gov/pubmed/30402094
http://dx.doi.org/10.1155/2018/4109491
_version_ 1783364650733142016
author Akinyemi, Ayodele Jacob
Adeniyi, Philip Adeyemi
author_facet Akinyemi, Ayodele Jacob
Adeniyi, Philip Adeyemi
author_sort Akinyemi, Ayodele Jacob
collection PubMed
description Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis.
format Online
Article
Text
id pubmed-6196928
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-61969282018-11-06 Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats Akinyemi, Ayodele Jacob Adeniyi, Philip Adeyemi J Toxicol Research Article Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis. Hindawi 2018-10-08 /pmc/articles/PMC6196928/ /pubmed/30402094 http://dx.doi.org/10.1155/2018/4109491 Text en Copyright © 2018 Ayodele Jacob Akinyemi and Philip Adeyemi Adeniyi. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Akinyemi, Ayodele Jacob
Adeniyi, Philip Adeyemi
Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title_full Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title_fullStr Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title_full_unstemmed Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title_short Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats
title_sort effect of essential oils from ginger (zingiber officinale) and turmeric (curcuma longa) rhizomes on some inflammatory biomarkers in cadmium induced neurotoxicity in rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196928/
https://www.ncbi.nlm.nih.gov/pubmed/30402094
http://dx.doi.org/10.1155/2018/4109491
work_keys_str_mv AT akinyemiayodelejacob effectofessentialoilsfromgingerzingiberofficinaleandturmericcurcumalongarhizomesonsomeinflammatorybiomarkersincadmiuminducedneurotoxicityinrats
AT adeniyiphilipadeyemi effectofessentialoilsfromgingerzingiberofficinaleandturmericcurcumalongarhizomesonsomeinflammatorybiomarkersincadmiuminducedneurotoxicityinrats

Ejemplares similares