Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells

Cladribine (2CdA), a synthetic purine analog interfering with DNA synthesis, is a medication used to treat hairy cell leukemia (HCL) and B-cell chronic lymphocytic leukemia. Entinostat, a selective class I histone deacetylase (HDAC) inhibitor, shows antitumor activity in various human cancers, inclu...

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Detalles Bibliográficos
Autores principales: Wang, Bolun, Lyu, Hui, Pei, Shanshan, Song, Deye, Ni, Jiangdong, Liu, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197031/
https://www.ncbi.nlm.nih.gov/pubmed/29969371
http://dx.doi.org/10.1080/15384101.2018.1464849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197031/
https://www.ncbi.nlm.nih.gov/pubmed/29969371
http://dx.doi.org/10.1080/15384101.2018.1464849

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