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Alpha2beta1 Integrin (VLA-2) Protects Activated Human Effector T Cells From Methotrexate-Induced Apoptosis

β1 integrins are critical for T cell migration, survival and costimulation. The integrin α2β1, which is a receptor for collagen, also named VLA-2, is a major costimulatory pathway of effector T cells and has been implicated in arthritis pathogenesis. Herein, we have examined its ability to promote m...

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Detalles Bibliográficos
Autores principales:	Abderrazak, Amna, El Azreq, Mohammed-Amine, Naci, Dalila, Fortin, Paul R., Aoudjit, Fawzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197073/ https://www.ncbi.nlm.nih.gov/pubmed/30374344 http://dx.doi.org/10.3389/fimmu.2018.02269

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