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Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report
Cardiovascular disease is an important contributor to maternal mortality in both developing and developed countries. Systematic search for cardiac disease is usually not performed during pregnancy despite hypertensive disease, undiagnosed pulmonary hypertension and cardiomyopathies being recognized...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197088/ https://www.ncbi.nlm.nih.gov/pubmed/30483636 http://dx.doi.org/10.1080/20961790.2017.1325548 |
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author | Vadysinghe, Amal Nishantha Jayasooriya, Rankothge Pemasiri Gunatilake, G. Keerthi Kumara Sivasubramanium, Murugupillai |
author_facet | Vadysinghe, Amal Nishantha Jayasooriya, Rankothge Pemasiri Gunatilake, G. Keerthi Kumara Sivasubramanium, Murugupillai |
author_sort | Vadysinghe, Amal Nishantha |
collection | PubMed |
description | Cardiovascular disease is an important contributor to maternal mortality in both developing and developed countries. Systematic search for cardiac disease is usually not performed during pregnancy despite hypertensive disease, undiagnosed pulmonary hypertension and cardiomyopathies being recognized as major health problems in these settings. This article reported a 27-year-old female who was normal on clinical examination and basic investigations, and on an antenatal visit was found collapsed in the toilet of her house and was pronounced dead on admission to hospital. She was found to be in the 11th week of pregnancy and had no history of significant illness in the past. Autopsy did not reveal any obvious macroscopic pathology except for a significant amount of epicardial fat infiltrating into myocardium of right ventricle. Detailed histopathological examination of the heart demonstrated fibro-fatty replacement of the heart muscle. The cause of death was arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). ARVC/D can cause unexpected sudden death during pregnancy. Therefore, it is recommended that an ECG and echocardiogram be included as screening tests during antenatal follow-up to minimize preventable cardiac deaths like ARVC/D. |
format | Online Article Text |
id | pubmed-6197088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-61970882018-11-27 Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report Vadysinghe, Amal Nishantha Jayasooriya, Rankothge Pemasiri Gunatilake, G. Keerthi Kumara Sivasubramanium, Murugupillai Forensic Sci Res Case Report Cardiovascular disease is an important contributor to maternal mortality in both developing and developed countries. Systematic search for cardiac disease is usually not performed during pregnancy despite hypertensive disease, undiagnosed pulmonary hypertension and cardiomyopathies being recognized as major health problems in these settings. This article reported a 27-year-old female who was normal on clinical examination and basic investigations, and on an antenatal visit was found collapsed in the toilet of her house and was pronounced dead on admission to hospital. She was found to be in the 11th week of pregnancy and had no history of significant illness in the past. Autopsy did not reveal any obvious macroscopic pathology except for a significant amount of epicardial fat infiltrating into myocardium of right ventricle. Detailed histopathological examination of the heart demonstrated fibro-fatty replacement of the heart muscle. The cause of death was arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). ARVC/D can cause unexpected sudden death during pregnancy. Therefore, it is recommended that an ECG and echocardiogram be included as screening tests during antenatal follow-up to minimize preventable cardiac deaths like ARVC/D. Taylor & Francis 2017-05-23 /pmc/articles/PMC6197088/ /pubmed/30483636 http://dx.doi.org/10.1080/20961790.2017.1325548 Text en © 2017 The Author(s). Published by Taylor & Francis Group on behalf of the Institute of Forensic Science, Ministry of Justice, People's Republic of China http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Vadysinghe, Amal Nishantha Jayasooriya, Rankothge Pemasiri Gunatilake, G. Keerthi Kumara Sivasubramanium, Murugupillai Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title | Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title_full | Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title_fullStr | Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title_full_unstemmed | Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title_short | Unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
title_sort | unexpected sudden death in pregnancy – arrhythmogenic right ventricular cardiomyopathy/dysplasia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197088/ https://www.ncbi.nlm.nih.gov/pubmed/30483636 http://dx.doi.org/10.1080/20961790.2017.1325548 |
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