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First report of carbapenem-resistant Providencia stuartii in Saudi Arabia

We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (ta...

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Autores principales: Abdallah, M., Alhababi, R., Alqudah, N., Aldyyat, B., Alharthy, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197148/
https://www.ncbi.nlm.nih.gov/pubmed/30364596
http://dx.doi.org/10.1016/j.nmni.2018.09.007
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author Abdallah, M.
Alhababi, R.
Alqudah, N.
Aldyyat, B.
Alharthy, A.
author_facet Abdallah, M.
Alhababi, R.
Alqudah, N.
Aldyyat, B.
Alharthy, A.
author_sort Abdallah, M.
collection PubMed
description We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia.
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spelling pubmed-61971482018-10-24 First report of carbapenem-resistant Providencia stuartii in Saudi Arabia Abdallah, M. Alhababi, R. Alqudah, N. Aldyyat, B. Alharthy, A. New Microbes New Infect First Clinical Case in Emerging Country We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia. Elsevier 2018-09-20 /pmc/articles/PMC6197148/ /pubmed/30364596 http://dx.doi.org/10.1016/j.nmni.2018.09.007 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle First Clinical Case in Emerging Country
Abdallah, M.
Alhababi, R.
Alqudah, N.
Aldyyat, B.
Alharthy, A.
First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title_full First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title_fullStr First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title_full_unstemmed First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title_short First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
title_sort first report of carbapenem-resistant providencia stuartii in saudi arabia
topic First Clinical Case in Emerging Country
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197148/
https://www.ncbi.nlm.nih.gov/pubmed/30364596
http://dx.doi.org/10.1016/j.nmni.2018.09.007
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