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First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (ta...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197148/ https://www.ncbi.nlm.nih.gov/pubmed/30364596 http://dx.doi.org/10.1016/j.nmni.2018.09.007 |
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author | Abdallah, M. Alhababi, R. Alqudah, N. Aldyyat, B. Alharthy, A. |
author_facet | Abdallah, M. Alhababi, R. Alqudah, N. Aldyyat, B. Alharthy, A. |
author_sort | Abdallah, M. |
collection | PubMed |
description | We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia. |
format | Online Article Text |
id | pubmed-6197148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-61971482018-10-24 First report of carbapenem-resistant Providencia stuartii in Saudi Arabia Abdallah, M. Alhababi, R. Alqudah, N. Aldyyat, B. Alharthy, A. New Microbes New Infect First Clinical Case in Emerging Country We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia. Elsevier 2018-09-20 /pmc/articles/PMC6197148/ /pubmed/30364596 http://dx.doi.org/10.1016/j.nmni.2018.09.007 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | First Clinical Case in Emerging Country Abdallah, M. Alhababi, R. Alqudah, N. Aldyyat, B. Alharthy, A. First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title_full | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title_fullStr | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title_full_unstemmed | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title_short | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
title_sort | first report of carbapenem-resistant providencia stuartii in saudi arabia |
topic | First Clinical Case in Emerging Country |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197148/ https://www.ncbi.nlm.nih.gov/pubmed/30364596 http://dx.doi.org/10.1016/j.nmni.2018.09.007 |
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