Cargando…
MicroRNA-10a promotes granulosa cells tumor development via PTEN-AKT/Wnt regulatory axis
We have previously reported that microRNA-10 family could disturb normal development of granulosa cells (GC) during follicle formation. In the current study, the effect of miR-10a on granulosa cell tumor (GCT), a subtype of ovarian cancer, was examined. Strong miR-10a signal was detected in tissues...
Autores principales: | Tu, Jiajie, Cheung, Hoi-Hung, Lu, Gang, Chen, Zijiang, Chan, Wai-Yee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197200/ https://www.ncbi.nlm.nih.gov/pubmed/30348959 http://dx.doi.org/10.1038/s41419-018-1117-5 |
Ejemplares similares
-
microRNA-126 Is a Tumor Suppressor of Granulosa Cell Tumor Mediated by Its Host Gene EGFL7
por: Tu, Jiajie, et al.
Publicado: (2019) -
The Role of microRNAs in Ovarian Granulosa Cells in Health and Disease
por: Tu, Jiajie, et al.
Publicado: (2019) -
Conserved miR-10 family represses proliferation and induces apoptosis in ovarian granulosa cells
por: Jiajie, Tu, et al.
Publicado: (2017) -
MicroRNA profiling during directed differentiation of cortical interneurons from human‐induced pluripotent stem cells
por: Tu, Jiajie, et al.
Publicado: (2018) -
MicroRNA-182 Regulates Neurite Outgrowth Involving the PTEN/AKT Pathway
por: Wang, Wu M., et al.
Publicado: (2017)