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Detection of a new reaction by-product in BDDE cross-linked autoclaved hyaluronic acid hydrogels by LC–MS analysis

BACKGROUND: Hyaluronic acid (HA), a naturally occurring polysaccharide, is used in the production of dermal fillers for esthetic purposes. As it has a few days of half-life in human tissues, HA-based dermal filler is chemically modified to increase its lifetime in the body. The most common modificat...

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Detalles Bibliográficos
Autores principales: Fidalgo, Javier, Deglesne, Pierre-Antoine, Arroyo, Rodrigo, Sepúlveda, Lilian, Ranneva, Evgeniya, Deprez, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197218/
https://www.ncbi.nlm.nih.gov/pubmed/30410412
http://dx.doi.org/10.2147/MDER.S166999

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