Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice

Autophagy activation improves the phenotype in mdx mice, a Duchenne muscular dystrophy (DMD) model, although the underlying mechanisms are obscure. We previously found that resveratrol, a strong inducer of autophagy, ameliorates the cardiac pathology of mdx mice. Autophagy could eliminate damaged mi...

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Detalles Bibliográficos
Autores principales: Kuno, Atsushi, Hosoda, Ryusuke, Sebori, Rio, Hayashi, Takashi, Sakuragi, Hiromi, Tanabe, Mika, Horio, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197260/
https://www.ncbi.nlm.nih.gov/pubmed/30348945
http://dx.doi.org/10.1038/s41598-018-33930-w

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