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NEDDylation promotes nuclear protein aggregation and protects the Ubiquitin Proteasome System upon proteotoxic stress

Spatial management of stress-induced protein aggregation is an integral part of the proteostasis network. Protein modification by the ubiquitin-like molecule NEDD8 increases upon proteotoxic stress and it is characterised by the formation of hybrid NEDD8/ubiquitin conjugates. However, the biological...

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Detalles Bibliográficos
Autores principales:	Maghames, Chantal M., Lobato-Gil, Sofia, Perrin, Aurelien, Trauchessec, Helene, Rodriguez, Manuel S., Urbach, Serge, Marin, Philippe, Xirodimas, Dimitris P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197266/ https://www.ncbi.nlm.nih.gov/pubmed/30349034 http://dx.doi.org/10.1038/s41467-018-06365-0

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