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Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Turkish Association of Orthopaedics and Traumatology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197303/ https://www.ncbi.nlm.nih.gov/pubmed/27817975 http://dx.doi.org/10.1016/j.aott.2016.08.018 |
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author | Karaoğlu, Sinan Karaaslan, Fatih Mermerkaya, Musa Uğur |
author_facet | Karaoğlu, Sinan Karaaslan, Fatih Mermerkaya, Musa Uğur |
author_sort | Karaoğlu, Sinan |
collection | PubMed |
description | Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admitted complaining of worsening chronic pain in his left knee. A radiographic evaluation showed tricompartmental end- stage osteoarthritis. A cemented total knee replacement was performed. At the 10-year follow-up, he had returned to full activity, had no knee pain, and was very satisfied with the outcome. No abnormality was observed in the femoral, tibial, or patellar components on radiography. We believe that total knee replacement is a good option in a patient with marked degenerative arthritis secondary to ochronotic arthritis. |
format | Online Article Text |
id | pubmed-6197303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Turkish Association of Orthopaedics and Traumatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-61973032018-10-24 Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy Karaoğlu, Sinan Karaaslan, Fatih Mermerkaya, Musa Uğur Acta Orthop Traumatol Turc Case Report Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admitted complaining of worsening chronic pain in his left knee. A radiographic evaluation showed tricompartmental end- stage osteoarthritis. A cemented total knee replacement was performed. At the 10-year follow-up, he had returned to full activity, had no knee pain, and was very satisfied with the outcome. No abnormality was observed in the femoral, tibial, or patellar components on radiography. We believe that total knee replacement is a good option in a patient with marked degenerative arthritis secondary to ochronotic arthritis. Turkish Association of Orthopaedics and Traumatology 2016-10 2016-11-03 /pmc/articles/PMC6197303/ /pubmed/27817975 http://dx.doi.org/10.1016/j.aott.2016.08.018 Text en © 2016 Publishing services by Elsevier B.V. on behalf of Turkish Association of Orthopaedics and Traumatology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Karaoğlu, Sinan Karaaslan, Fatih Mermerkaya, Musa Uğur Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title | Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title_full | Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title_fullStr | Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title_full_unstemmed | Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title_short | Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
title_sort | long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197303/ https://www.ncbi.nlm.nih.gov/pubmed/27817975 http://dx.doi.org/10.1016/j.aott.2016.08.018 |
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