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Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy

Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admi...

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Autores principales: Karaoğlu, Sinan, Karaaslan, Fatih, Mermerkaya, Musa Uğur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Association of Orthopaedics and Traumatology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197303/
https://www.ncbi.nlm.nih.gov/pubmed/27817975
http://dx.doi.org/10.1016/j.aott.2016.08.018
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author Karaoğlu, Sinan
Karaaslan, Fatih
Mermerkaya, Musa Uğur
author_facet Karaoğlu, Sinan
Karaaslan, Fatih
Mermerkaya, Musa Uğur
author_sort Karaoğlu, Sinan
collection PubMed
description Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admitted complaining of worsening chronic pain in his left knee. A radiographic evaluation showed tricompartmental end- stage osteoarthritis. A cemented total knee replacement was performed. At the 10-year follow-up, he had returned to full activity, had no knee pain, and was very satisfied with the outcome. No abnormality was observed in the femoral, tibial, or patellar components on radiography. We believe that total knee replacement is a good option in a patient with marked degenerative arthritis secondary to ochronotic arthritis.
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spelling pubmed-61973032018-10-24 Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy Karaoğlu, Sinan Karaaslan, Fatih Mermerkaya, Musa Uğur Acta Orthop Traumatol Turc Case Report Alkaptonuria is a rare metabolic disease caused by a partial or total deficiency of homogentisic acid oxidase, which results in excess homogentisic acid (HGA) levels. Homogentisic acid and its oxidation products can accumulate in hyaline cartilage, tendons, and ligaments. A 55-year-old male was admitted complaining of worsening chronic pain in his left knee. A radiographic evaluation showed tricompartmental end- stage osteoarthritis. A cemented total knee replacement was performed. At the 10-year follow-up, he had returned to full activity, had no knee pain, and was very satisfied with the outcome. No abnormality was observed in the femoral, tibial, or patellar components on radiography. We believe that total knee replacement is a good option in a patient with marked degenerative arthritis secondary to ochronotic arthritis. Turkish Association of Orthopaedics and Traumatology 2016-10 2016-11-03 /pmc/articles/PMC6197303/ /pubmed/27817975 http://dx.doi.org/10.1016/j.aott.2016.08.018 Text en © 2016 Publishing services by Elsevier B.V. on behalf of Turkish Association of Orthopaedics and Traumatology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Karaoğlu, Sinan
Karaaslan, Fatih
Mermerkaya, Musa Uğur
Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title_full Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title_fullStr Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title_full_unstemmed Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title_short Long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
title_sort long-term result of arthroplasty in the treatment of a case of ochronotic arthropathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197303/
https://www.ncbi.nlm.nih.gov/pubmed/27817975
http://dx.doi.org/10.1016/j.aott.2016.08.018
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