Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation

MicroRNA (miR) sponges containing miR binding sequences constitute a potentially powerful molecular therapeutic strategy. Recently, naturally occurring circular RNAs (circRNAs) were shown to function as efficient miR sponges in cancer cells. We hypothesized that synthetic circRNA sponges could achie...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Abraham, John M., Cheng, Yulan, Wang, Zhixiong, Wang, Zhe, Zhang, Guanjun, Ashktorab, Hassan, Smoot, Duane T., Cole, Robert N., Boronina, Tatiana N., DeVine, Lauren R., Talbot, C. Conover, Liu, Zhengwen, Meltzer, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197335/
https://www.ncbi.nlm.nih.gov/pubmed/30326427
http://dx.doi.org/10.1016/j.omtn.2018.09.010

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