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The influence of metabolic syndrome and its components on the development of nephrolithiasis

The prevalence of kidney stone disease is increasing, afflicting 7%–11% of the United States population. Multiple systemic conditions, including obesity and diabetes, are also on the rise. Further, the literature has demonstrated a strong association between metabolic syndrome, its components, and k...

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Detalles Bibliográficos
Autores principales: Boyd, Carter, Wood, Kyle, Whitaker, Dustin, Assimos, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197366/
https://www.ncbi.nlm.nih.gov/pubmed/30364536
http://dx.doi.org/10.1016/j.ajur.2018.06.002
Descripción
Sumario:The prevalence of kidney stone disease is increasing, afflicting 7%–11% of the United States population. Multiple systemic conditions, including obesity and diabetes, are also on the rise. Further, the literature has demonstrated a strong association between metabolic syndrome, its components, and kidney stone disease. In this article, we aim to review the associations of metabolic syndrome and nephrolithiasis, discussing the pathophysiology, urinary parameters, and clinical presentations. With this knowledge, urologists will have a more comprehensive understanding of this complex population of metabolic stone formers enabling improved patient management and treatment of stone disease.