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SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice

BACKGROUND: Sirtuin 5 (SIRT5) is a NAD(+)-dependent lysine deacylase. The SIRT5 deficiency mouse model shows that it is dispensable for metabolic homeostasis under normal conditions. However, the biological role of SIRT5 and acylation in pathological states such as obesity and type 2 diabetes (T2D)...

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Detalles Bibliográficos
Autores principales:	Du, Yipeng, Hu, Hao, Qu, Saisi, Wang, Jifeng, Hua, Chaoju, Zhang, Jialing, Wei, Peng, He, Xiaolong, Hao, Junfeng, Liu, Pingsheng, Yang, Fuquan, Li, Tingting, Wei, Taotao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197389/ https://www.ncbi.nlm.nih.gov/pubmed/30279144 http://dx.doi.org/10.1016/j.ebiom.2018.09.037

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