Characterization of Monoclonal Antibody–Protein Antigen Complexes Using Small-Angle Scattering and Molecular Modeling

The determination of monoclonal antibody interactions with protein antigens in solution can lead to important insights guiding physical characterization and molecular engineering of therapeutic targets. We used small-angle scattering (SAS) combined with size-exclusion multi-angle light scattering hi...

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Detalles Bibliográficos
Autores principales: Castellanos, Maria Monica, Snyder, James A., Lee, Melody, Chakravarthy, Srinivas, Clark, Nicholas J., McAuley, Arnold, Curtis, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197476/
https://www.ncbi.nlm.nih.gov/pubmed/30364605
http://dx.doi.org/10.3390/antib6040025

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