Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma

OBJECTIVE: The current obesity pandemic represents a major health burden, given that it predisposes to the development of numerous obesity-associated disorders. The obesity-derived adipokines not only impair systemic insulin action but also increase the incidence of hepatocellular carcinoma (HCC), a...

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Detalles Bibliográficos
Autores principales: Mittenbühler, Melanie J., Sprenger, Hans-Georg, Gruber, Sabine, Wunderlich, Claudia M., Kern, Lara, Brüning, Jens C., Wunderlich, F. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197506/
https://www.ncbi.nlm.nih.gov/pubmed/30224299
http://dx.doi.org/10.1016/j.molmet.2018.08.010

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