MALT lymphoma: epidemiology, clinical diagnosis and treatment

Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-c...

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Detalles Bibliográficos
Autores principales: Violeta Filip, Petruta, Cuciureanu, Denisa, Sorina Diaconu, Laura, Maria Vladareanu, Ana, Silvia Pop, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197515/
https://www.ncbi.nlm.nih.gov/pubmed/30364585
http://dx.doi.org/10.25122/jml-2018-0035
Descripción
Sumario:Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.

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